Mononucleosis, also known commonly as mono, is a viral illness. Mononucleosis infecciosa mono, mononucleosis veb english version. A recent example is that 1037 90% of 1148 subjects 18 and 19 years old participating in the u. In young adults, the disease often results in fever, sore throat, enlarged lymph nodes in the neck, and tiredness.
Infectious mononucleosis is a clinical entity characterized by pharyngitis, cervical lymph node enlargement, fatigue and fever, which results most often from a primary epsteinbarr virus ebv. Infectious mononucleosis was recognized as a unique disease in the 1880s by nil filatov, a russian pediatrician, who called the syndrome idiopathic adenitis. As adolescents are presumably more likely to have high numbers of. Behandling av epsteinbarr virusrelaterade sjukdomar. We now know that the characteristic atypical lymphocytes, carefully described morphologically by downey and mckinlay, 2.
Im is a clinical syndrome caused by epsteinbarr virus. Mononucleosisinfecciosa fernando lahoz garcia maria jose malo eguren 2. Es una enfermedad infecciosa, aguda, febril y autolimitada. Symptoms of mono can include, sore throat, swollen glands lymph nodesespecially. A handout on infectious mononucleosis, written by the author of this article, is provided on page 1289.
The virus infects a certain type of white blood cell called b lymphocytes. Luzuriaga k, sullivan jl 2010 infectious mononucleosis. Infectious mononucleosis is caused by epsteinbarr virus ebv, human herpesvirus type 4 and is characterized by fatigue, fever, pharyngitis, and lymphadenopathy. See page 1201 for definitions of strengthofrecommendation labels. Mononucleosis infecciosa enfermedades infecciosas manual.
However, our sample comes from the paediatric population, that is, the. Infective mononucleosis is most commonly caused by. Infectious mononucleosis disease fact sheet spanish. Mononucleosis infecciosa fundamentos del diagnostico.
Lara, mononucleosis infecciosa 75 revista medica dd 25 3809 11. While it is true that the epsteinbarr virus ebv is responsible for 85 percent of mono diagnoses and can be contracted from another persons saliva, a teenager might acquire it through drinking out of the same glass or sharing a straw with a person who is infected. Pdf infectious mononucleosis im or mononucleosis syndrome is caused by an. Infectious mononucleosis im, mono, also known as glandular fever, is an infection usually. Mononucleosis fact sheet infectious mononucleosis mono is caused by a virus the epsteinbarr virus ebv that causes mononucleosis is a type of herpes virus. Infectious mononucleosis is a clinical syndrome that is most commonly associated. Rafailidis pi, mavros mn, kapaskelis a, falagas me 2010.
Whereas most ebv infections of infants and children are. For example, rates of seroprevalence among children 5 to 9 years of age in urban. Infectious mononucleosis is the name coined by sprunt and evans in 1920 1 for an acute infectious disease consisting of fever, cervical lymphadenopathy and pharyngitis accompanied by atypical large peripheral blood lymphocytes. Pdf this journal feature begins with a case vignette highlighting a common clinical problem. She appears very tired and has a temperature of 39c. Severe complications, including airway obstruction, splenic rupture, and neurologic syndromes, occasionally occur. Mono is caused by epsteinbarr virus ebv, a member of the herpesvirus family. The familiar nickname for mononucleosis or mono, the kissing disease, is somewhat misleading. Pdf clinical and laboratory characteristics of infectious.
The viru s is shed in saliva and spreads through direct contact. Infectious mononucleosis im, mono, also known as glandular fever, is an infection usually caused by the epsteinbarr virus ebv. Infectious mononucleosis infectious diseases msd manual. Mononucleosis mono fact sheet what is mononucleosis mono. Infectious mononucleosis, mononucleosis syndrome, epsteinbarr virus. Infectious mononucleosis is a viral illness in most cases, and as such it can be treated with rest, hydration, analge sia, and antipyretics. Pdf clinical and laboratory differences between epsteinbarr and. Most people are infected by the virus as children, when the disease produces few or no symptoms. A 16yearold, previously healthy girl presents with a severalday history of fever, sore throat, and malaise. Feb, 2015 mononucleosis infecciosa somos vid duration. Vyas, md, phd, assistant professor in medicine, harvard medical school.
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